Pharmacodynamics igice cya sintetike ya macrolide antibiyotike yinyamaswa zo mu bwoko bwa temicosine. Irakomeye kuri mycoplasma, kandi ingaruka zayo zirwanya tylosine. Indwara ya bagiteri yoroheje ni staphylococcus aureus (harimo na penisiline irwanya staphylococcus aureus), pneumococcus, streptococcus, anthrax bacillus, swineerysipelas, listeria, clostridium putrefaciens, clostridium emphysema nibindi. Indwara ya bacteri yunvikana ni haemophilus, meningococci, pasteurella kandi vuba. Igikorwa cyo kurwanya actinobacillus pleuropneumoniae, pasteurella na mycoplasma y’amatungo n’inkoko kirakomeye kuruta tylosine. 95% bya pasteurella hemolyticus yumvaga ibicuruzwa.
Pharmacokinetic yihuta kwinjizwa nyuma yubuyobozi bwimbere, irangwa no kwinjiza ingirabuzimafatizo zikomeye, ubwinshi bwo gukwirakwiza (burenze 2l / kg). Ubwinshi buri mu bihaha, kurandura igice cyubuzima bushobora kugera ku minsi 1 ~ 2, kandi kwibanda kumaraso neza bikomeza igihe kirekire.
(1) Guhuza ibicuruzwa na epinephrine birashobora kongera urupfu rwingurube.
(2) Ifite intego imwe nizindi macrolide na lincoamine, kandi ntigomba gukoreshwa icyarimwe.
(3) Gukomatanya β-lactam byerekana ingaruka zo kurwanya.
Antibiyotike ya Macrolide. Ikoreshwa mu kuvura actinobacillus, pasteurella na mycoplasma kwandura porcine pleuropneumoniae.
Kugaburira bivanze: ingurube 1000 ~ 2000g kuri 1000 kg ibiryo 15.
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