Pharmacodynamics enrofloxacin ni imiti yagutse ya bagiteri yica inyamaswa zo mu bwoko bwa fluoroquinolone. Ifite ingaruka nziza kuri escherichia coli, salmonella, klebsiella, brucella, pasteurella, actinobacillus pleuropneumoniae, erysipelas, proteus, serratia marcescens, corynebacterium pyogène, portococcus septicus, staphylococcus aureus pseudomonas aeruginosa na streptococcus, n'ingaruka nke kuri bagiteri ya anaerobic. Ifite ingaruka nyuma ya antibacterial kuri bagiteri zoroshye. Uburyo bwa antibacterial yiki gicuruzwa nuguhagarika bagiteri dna rotation enzyme, kubangamira kwigana kwa bagiteri, kwandukura no gusana ibyiyumvo, bagiteri ntishobora gukura no kubyara bisanzwe kandi igapfa.
Pharmacokinetics iyinjizwa ryibicuruzwa byihuta kandi byuzuye, hamwe na bioavailable ya 91.9% mu ngurube na 82% mu nka zinka. Ikwirakwizwa cyane mu nyamaswa kandi irashobora kwinjira neza mu ngingo no mu mazi yo mu mubiri, usibye amazi yo mu bwonko, ubwinshi bw'imiti mu ngingo hafi ya zose ziri hejuru kuruta iyo muri plasma. Umwijima metabolism ni ugukora cyane ciprofloxacin ukuraho Ethyl yimpeta 7-piperazine, ikurikirwa na okiside hamwe na aside glucuronic. Isohora cyane cyane impyiko (no gusohora impyiko zimpyiko no kuyungurura glomerular), naho 15% kugeza 50% isohoka mu nkari muburyo bwumwimerere. Kurandura igice cyubuzima buratandukanye cyane muburyo butandukanye n'inzira zitandukanye z'ubuyobozi. Kurandura igice cyubuzima nyuma yo guterwa inshinge ni amasaha 5.9 mu nka, amasaha 9.9 mumafarasi, amasaha 1.5 kugeza 4.5 mu ntama, namasaha 4,6 mu ngurube.
1.Ibicuruzwa bifite ingaruka zo guhuza iyo bikoreshejwe na aminoglycoside cyangwa penisiline yagutse.
2.Icyuma gikomeye ion nka ca2 +, mg2 +, fe3 + na al3 + canchelate hamwe niki gicuruzwa kandi bigira ingaruka kumitsi.
3. Iyo ihujwe na theophylline na cafine, irashobora kugabanya igipimo cyo guhuza poroteyine ya plasma, kongera mu buryo budasanzwe kwibumbira hamwe kwa teofiline na cafine mu maraso, ndetse bikagaragaza ibimenyetso by’uburozi bwa teofiline.
4. Iki gicuruzwa gifite ingaruka zo guhagarika imisemburo y’imiti y’umwijima, ishobora kugabanya igipimo cy’imiti y’ibiyobyabwenge cyane cyane ihinduranya umwijima kandi ikongera ibiyobyabwenge mu maraso.
Imiti ya antibacterial Fluoroquinolone. Ikoreshwa mu bworozi bw'amatungo n'inkoko n'indwara ya mycoplasma.
Gutera inshinge: Igipimo kimwe, 0,025ml kuri 1 kg uburemere bwumubiri winka, intama ningurube; 0.025 ~ 0.05ml ku mbwa, injangwe n'inkwavu. Koresha inshuro 1 kugeza kuri 2 kumunsi muminsi 2 kugeza 3.
1. Kwangirika kwa karitsiye mu nyamaswa zikiri nto, bigira ingaruka kumikurire yamagufa no gutera ubumuga nububabare.
2. Imyitwarire ya sisitemu igogora irimo kuruka, kubura ubushake bwo kurya, impiswi kandi vuba.
3. Ibisubizo byuruhu birimo erythema, pruritus, urticaria na fotosensitivite.
4. Imyitwarire ya allergie, ataxia, gufatwa bigaragara mu mbwa ninjangwe.
1. Ifite ingaruka zishimishije kuri sisitemu yo hagati, itera igicuri, kandi igomba gukoreshwa ubwitonzi mu mbwa z'igicuri.
2. Inyamanswa n’inyamaswa zifite imikorere mibi yimpyiko zigomba gukoreshwa ubwitonzi, zishobora rimwe na rimwe gutera inkari za kristaline.
3. Iki gicuruzwa ntikibereye amafarasi. Gutera inshinge ni ibintu bitera inzibacyuho.
4. Iki gicuruzwa ntigikwiye gukoreshwa mu mbwa mbere yibyumweru 8.
5. Imiti irwanya imiti yiki gicuruzwa iriyongera kandi ntigomba gukoreshwa muri dosiye ya subtherapeutic igihe kirekire.
